DiPIA 2020 – Postponed to 2021
Developments in Protein Interaction Analysis


28–1 July 2021  
Uppsala Konsert & Kongress, Uppsala, Sweden.

Real science, real interactions, real time
Don’t miss out on the latest developments in biophysical characterization.

  • Be inspired by real science presented by fellow researchers
  • Engage and benefit from real interactions with leading experts
  • Learn tips and techniques in biophysical characterization

DiPIA attracts delegates and speakers from around the world. Interact with your peers from academia and industry who will share their insights in areas from basic research to quality control using Biacore systems.

Hear your fellow researchers’ impressions of DiPIA 2018…

Taylor-Anne Gorman Sartorius Stedim BioOutsource

Nanting Ni Sanofi Genzyme

Markus Sack Pro-SPR GmbH

Conference topics Download full agenda

Biotherapeutics/biologics

Therapeutic antibodies are one of the fast growing classes of biopharmaceuticals and this trend is set to continue with the development of new classes of therapeutic antibodies, bioconjugates, and vaccines.


Session I: Characterization of biotherapeutics
This session will showcase the role of Biacore systems in the discovery, development, and analysis of biotherapeutics and how SPR is used to identify, quantitate, and characterize the biotherapeutic drugs of tomorrow.

Session II: Non-traditional biotherapeutic formats—advanced characterization options
This session will cover how Biacore systems are used in development of new biotherapeutics—from alternative scaffolds and functionalization for antibodies to nanoparticles and DNA-antigens for vaccines.

Analytical development and quality control (QC)

Over the past years, there has been a significant increase in the use of label-free, real-time SPR binding assays in process and late-stage analytical development as well as quality control. Listen to how SPR is being used for drug product characterization and quality control.


Session I: Implementation and validation of GMP-compliant release assays
This session will provide insights on how Biacore assays have been successfully adopted for better product characterization, comparability, and stability assessment including FDA-approved release testing and will supported with cases studies for a wide range of drug classes.

Session II: Novel approaches to improve characterization and QC of complex biologics
In-depth understanding of critical quality attributes and how different bioprocess conditions impact these attributes is crucial for confident decision-making from R&D to QC. The session will show how innovative SPR methodologies have been implemented and validated in analytical development to support characterization of complex next-generation biologics as well as biosimilars.

Low molecular weight (LMW) drug discovery and characterization

SPR delivers the high sensitivity needed to detect LMW and low affinity compounds binding to their targets. This makes SPR the analysis technique of choice for early stage fragment-based drug discovery, hit screening, and for detailed characterization of novel lead compounds.


Session I: Fragment and LMW compounds screening and characterization
This session will highlight how SPR can be employed in drug discovery from the early stages of fragment-based screening through to detailed characterization of novel lead compounds, enabling well-informed decisions about lead candidates.

Session II: novel target classes and mode of actions in LMW drug discovery
New classes of small molecules have emerged in recent years to target difficult and undruggable targets such as targeted protein degradation activators and stabilizers.

Advanced research applications

SPR is used for a range of application areas beyond core drug discovery, providing everything from qualitative, comparative data to quantitative data. All of this helps to improve our understanding of the mechanisms of action. This session aims to demonstrate the broad spectrum of applications that can be investigated with Biacore systems.


Session I: Beyond drug discovery
This session will highlight the use of Biacore systems in several different application areas, detailing the varying types of information that can be obtained with optical biosensors. The session describes how this information is used to further research, support hypotheses, or deliver diagnoses.
Session II: Insights into mechanisms of action
Binding mechanisms can be anything from regulation of gene expression to cell activation, for example, by binding to surface receptors, activation of enzymes, membrane fusion, complex formation, or inducing structural changes in molecules. This session will highlight how SPR is used to provide further insight into biologic pathways and mechanisms of action.

DiPIA 2018

Present a scientific poster

Share your new research by presenting a poster at DiPIA 2020. All selected posters are displayed in the exhibit and poster hall area for the duration of conference.

Poster abstracts should be no more than 500 words and must describe original work; they should contain the author’s name, affiliation, email address, topic, and description. Please note that all poster presenters must be registered attendees.

The deadline for submitting your abstract is 1 May 2021. Please submit to the following contact email: [email protected]

Tutorials

Kick off DiPIA by attending one of the Tutorial Sessions on Monday, 22 June. Join our R&D team and application specialists to learn new uses and applications for SPR and the latest in data analysis and software. Tutorial topics include:

  • How to design and validate an SPR assay
  • Streamline all Biacore data analysis using same evaluation software
  • Frequent challenges and solutions for SPR assay developers


Join our pre-conference tutorials at no extra cost on Monday, 22 June 2020.

Workshops

Workshops are an opportunity to dive deeper into Biacore analysis and learn helpful tips and tricks. Workshop sessions will showcase challenges and success stories of working with biotherapeutics and small molecules.

  • Biotherapeutics: This session will highlight implementation of Biacore systems in various stages of biotherapeutic discovery, characterization, and development including epitope binning, kinetics/affinity, and surrogate potency assays
  • Small Molecule: This session will focus on assay development, working with challenging drug targets, structure activity and kinetics relationships, and modeling complex mechanisms of action

Registration fee


Registration
9500 SEK
  • Regular pricing from
    April–June

Early registration
8500 SEK

One day pass
3200 SEK
  • 28 June
    (Including Welcome reception)
  • 29, 30 June or 1 July
    Scientific presentations and exhibition
    (excluding Gala dinner on 30 June)
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